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| Product Name | NPM1, 1-294aa, Human, His tag, E Coli |
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| Description | MW: 34.7kDa (314aa), confirmed by MALDI-TOF. Purity >85% by SDS-PAGE. NPM1 is a phosphoprotein which moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia. Recombinant human NPM1 protein, fused to His-tag at N-terminus, was |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Nucleophosmin; B23; NPM] |
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| Gene, Accession, CAS # | NPM1, Gene ID: 4869, Accession: NP_002511 |
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| Catalog # | MBS204570 |
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| Order / More Info | NPM1, 1-294aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Sagawa,F., et al. (2011) EMBO J. 30 (19), 3994-4005.; Neubauer,A., et al. (2011) Exp. Hematol. 39 (10), 1030-1042. |
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