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Product Name | PAF Acetylhydrolase Activity Assay Kit (Colorimetric) |
Description | Platelet-Activating Factor (PAF or 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is an important phospholipid mediator, which has diverse biological activities. PAF is synthesized and secreted by a variety of cells such as mast cells, monocytes, macrophages etc. Upregulated PAF signaling can cause pathological inflammation and also has been found to be responsible for sepsis, shock, and traumatic injury. PAF Acetylhydrolase (PAF-AH or 1-alkyl-2-acetylglycerophosphocholine esterase or Lipoprotein-associated phospholipase A2 or Lp-PLA2) (EC 3.1.1.47) hydrolyzes PAF by removing acetyl group at the sn-2 position and converts PAF into biologically inactive form, lyso-PAF. PAF-AH has two forms: extracellular and intracellular that shares some s |
Size | 100 assays |
Concentration | n/a |
Applications | • Measurement of PAF-AH activity in various samples• Study/characterize PAF-AH inhibitors or activators• Mechanistic study of inflammatory disorders |
Other Names | Platelet-Activating Factor Acetylhydrolase Activity Assay Kit (Colorimetric) |
Gene, Accession, CAS # | n/a |
Catalog # | K765-100 |
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Order / More Info | PAF Acetylhydrolase Activity Assay Kit (Colorimetric) from BIOVISION, INC. |
Product Specific References | n/a |
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