| 产品详情 |
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| Product Name | GSK2033 |
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| Description | An antagonist of LXRα and LXRβ (IC50s = 0.1 and 0.398 µM, respectively); inhibits LXR agonist-induced and basal expression of ABCA1 and SREBP-1c in THP-1 and HepG2 cells; binds promiscuously to a variety of nuclear receptors including RORγ, RXRα, ERα, and ERβ in a nuclear receptor specificity assay in HEK293 cells; induces the expression of fatty acid synthase and SREBP-1 in a mouse model of NAFLD |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GSK-2033 LXR-α β ABCA-1 SREBP1c THP1 HepG-2 ROR-γ α ER-α β RXR |
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| Gene, Accession, CAS # | CAS: 1221277-90-2 |
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| Catalog # | 25443-5 |
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| Order / More Info | GSK2033 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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