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Product Name | Phlorizin |
Description | Phlorizin is a competitive inhibitor of SGLT1 (sodium glucose co-transporter 1) and SGLT2 (sodium glucose co-transporter 2); this reduces renal glucose transport, lowering the amount of glucose in the blood. It competitively inhibits the initial rate of α-methyl-D-glucopyranoside (α-MDG) uptake in human COS-1 cells expressing hSGLT1 and hSGLT2 with IC50 values of 400 and 65 nM, respectively. In HEK293T cells expressing human SGLT1 and SGLT2, phlorizin exhibits Ki values of 140 and 11 nM, respectively, at 37°C. MW: 436.41. Purity ≥98% |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-?[2-?(β-?D-?glucopyranosyloxy)-?4,?6-?dihydroxyphenyl]-?3-?(4-?hydroxyphenyl)-?1-?propanone; NSC 2833; Florizidin |
Gene, Accession, CAS # | CAS: 60-81-1 |
Catalog # | 2416-100 |
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Order / More Info | Phlorizin from BIOVISION, INC. |
Product Specific References | n/a |
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