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| Product Name | PX 12 |
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| Description | Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo. Purity 99%. MW (observed): 188.31 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[(1-Methylpropyl)dithio]-1H-imidazole. IV-2 |
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| Gene, Accession, CAS # | CAS: 141400-58-0 |
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| Catalog # | 2954/10 |
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| Price | |
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| Order / More Info | PX 12 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22463935, 24260080 |
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| 产品资料 |
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