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| Product Name | KAT2A (GCN5), Active |
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| Description | 323-end. MW: ~82 kDa. Description: Recombinant human KAT2A (GCN5) (323-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: KAT2A (K (lysine) acetyltransferase 2A) is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator which functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner (1). KAT2A control chromosome stability by coordinating |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Acetyltransferase Assay |
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| Other Names | [Homo sapiens lysine acetyltransferase 2A (KAT2A), mRNA; Histone acetyltransferase KAT2A; histone acetyltransferase KAT2A; lysine acetyltransferase 2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97] |
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| Gene, Accession, CAS # | KAT2A, Gene ID: 2648, Accession: NM_021078.2 |
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| Catalog # | MBS515518 |
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| Order / More Info | KAT2A (GCN5), Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Mao, X. et.al: GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappa-B/RelA. Genes Dev. 23: 849-861, 2009. 2. Xu, W. et.al: Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates. Molec. Cell. Biol. 18: 5659-5669, 1998. |
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