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Product Name | SU 5402 |
Description | Potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively). Inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo. Also attenuates integrin β4-induced differentiation of neural stem cells. Purity 95%. MW (observed): 296.32 |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid |
Gene, Accession, CAS # | CAS: 215543-92-3 |
Catalog # | 3300/1 |
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Order / More Info | SU 5402 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21359200, 21419761, 22553035, 22791896, 23250206, 23536566, 24333178, 24336047, 24531379, 24803652, 25212830, 25894690, 26368825, 26420862, 28270602 |
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