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| Product Name | SU 9516 |
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| Description | Cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 0.02 - 0.03, 0.04 - 0.2, 0.2 - 1.7 and 0.9 μM for cdk2, cdk1, cdk4 and cdk9, respectively). Inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest. Transcriptionally downregulates Mcl-1 and has antiproliferative, cytostatic and pro-apoptotic effects in vitro. Purity 99%. MW (observed): 241.25 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (Z)-1,3-Dihydro-3-(1H-imidazol-4-ylmethylene)-5-methoxy-2H-indol-2-one |
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| Gene, Accession, CAS # | CAS: 377090-84-1 |
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| Catalog # | 2907/10 |
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| Order / More Info | SU 9516 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25124967 |
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| 产品资料 |
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