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| Product Name | TPM3-ALK Mutant, Active |
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| Description | 1-258 (TPM3) - 1058-end (ALK). MW: ~125 kDa. Description: Recombinant human fusion protein TPM3 (1-258)-ALK (1058-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: ALK or CD246 is a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. CD246 plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. ALK-positive neoplasms represent a distinct entity bec |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [Homo sapiens tropomyosin 3 (TPM3), transcript variant Tpm3.12, mRNA; Tropomyosin alpha-3 chain; tropomyosin alpha-3 chain; tropomyosin 3; Gamma-tropomyosin; Tropomyosin-3; Tropomyosin-5; hTM5] |
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| Gene, Accession, CAS # | TPM3-ALK, Gene ID: 7170, Accession: NM_152263.3 |
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| Catalog # | MBS515449 |
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| Order / More Info | TPM3-ALK Mutant, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Benharroch, D.et.al: ALK-positive lymphoma: a single disease with a broad spectrum of morphology. Blood 91: 2076-2084, 1998. 2. Giuriato S. et al: Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia. Blood. 2010 May 20; 115 (20): 4061-70. |
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