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| Antigenic Specificity | Cytokeratin 8 |
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| Clone | 8A5D12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cytokeratin 8 Monoclonal Antibody (8A5D12). This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
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| Immunogen | n/a |
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| Other Names | K8; KO; CK8; CYK8; K2C8; CARD2; KRT8 |
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| Gene, Accession # | Entrez: 3856; Uniprot: P05787 |
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| Catalog # | MA5-15460 |
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| Price | |
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| Order / More Info | Cytokeratin 8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25222612 |
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