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| Product Name | nTZDpa |
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| Description | Potent, selective non-thiazolidinedione PPARγ partial agonist (EC50 = 57 nM); produces ~25% maximum efficacy. Antagonizes full agonist activity by ~60% (IC50 ~ 285 nM). Displays no activity at PPARα or PPARδ receptors. Produces altered receptor conformation, and regulates adipocyte development and gene expression, in a differential manner to full PPARγ agonists. Modulates metabolism and insulin sensitivity without causing cardiac hypertrophy in mice in vivo. Purity 98%. MW (observed): 428.33 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-Chloro-1-[(4-chlorophenyl)methyl]-3-(phenylthio)-1H-indole-2-carboxylic acid |
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| Gene, Accession, CAS # | CAS: 118414-59-8 |
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| Catalog # | 2150/10 |
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| Price | |
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| Order / More Info | nTZDpa from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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