| 产品详情 |
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| Antigenic Specificity | LYK5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LYK5 Polyclonal Antibody. LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1. |
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| Immunogen | n/a |
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| Other Names | STE20-related adaptor protein; STRAD alpha; Serologically defined breast cancer antigen NY-BR-96; STRAD |
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| Gene, Accession # | Entrez: 72149, 92335; Uniprot: Q3UUJ4, Q7RTN6 |
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| Catalog # | PA5-13943 |
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| Price | |
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| Order / More Info | LYK5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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