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| Product Name | Necrosis Inhibitor, Necrox-5 |
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| Description | A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1 µM NecroX-5 prevented ~50% cell death in H9C2 cells exposed to 400 µM t-BuOOH for 2 hours). Does not protect against staurosporine or etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro, as well as CCl4 -induced acute liver injury and chronic liver fibrosis in rodent models. MW: 645.83. Purity ≥95% by HPLC |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(tetrahydro-pyran-4-ylmethyl)-amine, dihydrochloride |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 2229-1 |
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| Order / More Info | Necrosis Inhibitor, Necrox-5 from BIOVISION, INC. |
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| Product Specific References | n/a |
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