| 产品详情 |
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| Antigenic Specificity | MB21D1 |
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| Clone | 7E3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 κ |
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| Format | Protein G purified |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MB21D1 (7E3) Monoclonal Antibody. • Target Background: Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Has antiviral activity by acting as a key cytosolic DNA sensor, the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses. Binds cytosolic DNA directly, l |
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| Immunogen | This MB21D1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-185 amino acids from human MB21D1. |
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| Other Names | cGAS; h-cGAS; C6orf150; Cyclic GMP-AMP synthase; cGAMP synthase; 2'3'-cGAMP synthase; Mab-21 domain-containing protein 1; MB21D1 |
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| Gene, Accession # | Gene ID: 115004, SwissProt: Q8N884 |
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| Catalog # | bsm-51379M |
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| Price | |
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| Order / More Info | MB21D1 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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