| 产品详情 |
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| Product Name | TNFRSF12A, 28-80aa, Human, hIgG-His-tag, Baculovirus |
| Description | MW: 32.6kDa (292aa) 28-40kDa (SDS-PAGE under reducing conditions). Purity >90% by SDS-PAGE. TNFRSF12A, also known as tumor necrosis factor receptor superfamily member 12A, is the sole signaling receptor for the proinflammatory cytokine TWEAK (TNFSF12). It is a Downstream Target of the TGF-b Signaling Pathway and regulates Fibroblast Activation. It promotes oxidative stress through NADPH oxidase activation in macrophages. It is responsible for TWEAK-induced proliferation of endothelial cells and |
| Size | 0.05 mg, 0.25 mg |
| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
| Applications | SDS-PAGE |
| Other Names | [Tumor necrosis factor receptor superfamily member 12A; TNFRSF12A; CD266; FN14; TWEAKR] |
| Gene, Accession, CAS # | TNFRSF12A, Gene ID: 51330, Accession: NP_057723 |
| Catalog # | MBS206674 |
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| Order / More Info | TNFRSF12A, 28-80aa, Human, hIgG-His-tag, Baculovirus from MYBIOSOURCE INC. |
| Product Specific References | Nakayama M., et al. (2003) J Immunol. 170:341-348.; Madrigal-Matute J., et al. (2015) Cardiovasc Res. 108:139-147. |
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