| 产品详情 |
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| Antigenic Specificity | PEN2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PEN2 Polyclonal Antibody. • Target Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity. |
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| Immunogen | KLH conjugated synthetic peptide derived from human PEN2. Immunogen Range: 1-50/101 |
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| Other Names | PEN2; PEN-2; MDS033; MSTP064; Gamma-secretase subunit PEN-2; Presenilin enhancer protein 2; PSENEN |
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| Gene, Accession # | Gene ID: 55851, SwissProt: Q9NZ42 |
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| Catalog # | bs-6456R |
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| Price | |
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| Order / More Info | PEN2 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Chu, Yanan, et al. (2015) Acta Biochim Biophys Sin (Shanghai). PubMed: 25736404 // Chu et al. (2015) Acta.Biochim.Biophys.Sin.(Shanghai). 47:258-66. PubMed: 25736404 |
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