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| Product Name | GSK2830371 |
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| Description | MW: 461.02. Purity ≥98% by HPLC. Background: GSK2830371 is an allosteric Wip1 (Wild type p53-induced phosphatase) inhibitor (IC?? of 6 nM). It binds to a flap subdomain that regulates Wip1's enzymatic activity and substrate recognition. Due to lack of this domain in other phosphatases, its binding to GSK2830371 results in a selective and potent inhibition of Wip1. Treatment of tumor cells with the inhibitor GSK2830371 increases phosphorylation of Wip1 substrates and causes growth inhibition i |
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| Size | 1 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [GSK-2830371] |
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| Gene, Accession, CAS # | CAS: 1404456-53-6 |
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| Catalog # | MBS842645 |
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| Price | |
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| Order / More Info | GSK2830371 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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