| 产品详情 |
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| Antigenic Specificity | O6-Methylguanine-DNA-Methyltransferase (MGMT) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O position of guanine, restoring guanine to its normal form without causing DNA breaks . MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents . It is ubiquitously expressed in normal human tissues and is overexpressed in many types of human tumors, but epigenetically silenced in other tumors. MGMT silencing is a marker associated with poor prognosis, but is a good predictive marker for response to alkylating agent chemotherapy . Synonyms: MGMT |
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| Immunogen | Recombinant protein of human MGMT |
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| Other Names | AGT|AI267024|Agat |
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| Gene, Accession # | Gene ID: 4255,17314,25332 |
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| Catalog # | ABIN1683776 |
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| Price | |
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| Order / More Info | O6-Methylguanine-DNA-Methyltransferase (MGMT) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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