| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Factor XII Light chain |
|---|
| Clone | C6B7 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 250 ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA: 1-10 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Factor XII Light chain Monoclonal Antibody (C6B7). This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves facto |
|---|
| Immunogen | n/a |
|---|
| Other Names | HAE3, HAEX, HAF |
|---|
| Gene, Accession # | Entrez: 2161; Uniprot: P00748 |
|---|
| Catalog # | MA1-10829 |
|---|
| Price | |
|---|
| Order / More Info | Factor XII Light chain Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|