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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 46.3kDa. Partial: 27-203aa. N-terminal GST-tagged. Homo sapiens (Human). Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Tumor necrosis factor receptor 2; TNF-R2Tumor necrosis factor receptor type II; TNF-RII; TNFR-IIp75p80 TNF-alpha receptor; CD120bINN: Etanercept |
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| Gene, Accession, CAS # | TNFRSF1B, UniProt: P20333 |
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| Catalog # | RPC25833 |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), partial from BIOMATIK |
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| Product Specific References | n/a |
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