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| Product Name | Iressa |
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| Description | Orally active, selective inhibitor of EGFR tyrosine kinase (IC50 = 23 - 79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. Also inhibits growth of brain metastases in mouse model of non-small cell lung cancer. View information regarding the usage of Iressa for non-clinical studies . Purity 98%. MW (observed): 446.9 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine. Gefitinib, ZD 1839 |
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| Gene, Accession, CAS # | CAS: 184475-35-2 |
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| Catalog # | 3000/10 |
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| Order / More Info | Iressa from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20471049, 22919280, 23894460, 24100792, 24464917, 24496038, 24644001, 24971999, 25484865, 25501339, 25761747, 25823819, 25946135, 26239082, 26317041, 26497205, 26909254, 26984042, 27125283 |
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