| 产品详情 |
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| Antigenic Specificity | STRO-1 |
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| Clone | STRO-1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgM |
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| Format | ion exchange chromatography purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10 % of mononuclear cells, greater than 90 % of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells. |
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| Immunogen | Human CD34 positive bone marrow cells |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN638439 |
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| Price | |
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| Order / More Info | STRO-1 Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 10027900, 11393789, 12665563, 14715641, 16183789, 19525367, 2070060 |
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