| 产品详情 |
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| Antigenic Specificity | Lamin A/C |
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| Clone | 4A7 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, rabbit |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Immunohistochemistry (Frozen): Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lamin A/C Monoclonal Antibody (4A7), eBioscience™. Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-t |
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| Immunogen | n/a |
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| Other Names | RP11-54H19.1, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, PRO1 |
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| Gene, Accession # | Entrez: 100343574, 100757316, 16905, 4000; Uniprot: P02545, P48678 |
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| Catalog # | 14-9688-80 |
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| Price | |
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| Order / More Info | Lamin A/C Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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