| 产品详情 |
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| Antigenic Specificity | NIK |
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| Clone | 3H31L48 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 4-6 µg/mL, Immunofluorescence: 4-6 µg/mL, Western Blot: 1:100-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NIK Antibody (3H31L48), ABfinity™ Rabbit Monoclonal. NIK, also known as mitogen-activated protein kinase kinase kinase (MAP3K) 14 is an NF-kappaB inducing protein kinase of the serine/threonine kinase family. NIK binds to Traf2 to activate NF-kappaB as part of a signaling cascade involving receptors of the TNF/NGF family and the interleukin-1 type-I receptor. NIK protein is shuttled between cytosolic, nuclear and nucleolar compartments. When shuttled to the nucleoli, NIK-dependant NF-kappaB activation is impaired relative to its nuclear localization revealing a possible means of regulation. Reactive oxygen species can interact directly with NIK to alter NF-kappaB activation. Additionally, NIK specifically interacts with Down syndrome |
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| Immunogen | n/a |
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| Other Names | FTDCR1B, HS, HSNIK, NIK, NF-kappa-beta-inducing kinase, serine/threonine protein-kinase, serine/threonine-protein kinase NIK |
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| Gene, Accession # | Entrez: 9020; Uniprot: Q99558 |
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| Catalog # | 700281 |
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| Price | |
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| Order / More Info | NIK Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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