| 产品详情 |
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| Antigenic Specificity | NIK |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NIK Polyclonal Antibody. Nuclear factor kappa B (NF-kappa-B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa-B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF-a, LPS and mitogens. A serine/threonine protein kinase which mediates NF-kappa-B activation by IL-1, TNF-a and CD95 was identified recently and designated NIK (for NF-kappa-B inducing kinase). NIK is an activator of Ikappa-B kinase alpha and beta (IKK-a and IKK-b). Therefore, NIK is a key molecule in the NF-kappa-B signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokine |
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| Immunogen | n/a |
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| Other Names | FTDCR1B, HS, HSNIK, NIK; NF-kappa-beta-inducing kinase; serine/threonine protein-kinase; serine/threonine-protein kinase NIK |
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| Gene, Accession # | Entrez: 9020; Uniprot: Q99558 |
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| Catalog # | PA5-19871 |
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| Price | |
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| Order / More Info | NIK Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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