| 产品详情 |
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| Product Name | SH2 Domain Containing 1A (SH2D1A) peptide |
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| Description | SH2D1A is a protein that plays a major role in the bidirectional stimulation of T and B cells. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in SH2D1A gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | DSHP|EBVS|IMD5|LYP|MTCP1|SAP|SAP/SH2D1A|XLP|XLPD|RGD1562408|Gm686|SH2D1A |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN936059 |
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| Price | |
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| Order / More Info | SH2 Domain Containing 1A (SH2D1A) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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