| 产品详情 |
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| Product Name | SMI-4a |
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| Description | A Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK, killing a wide range of both myeloid and lymphoid cell lines (with IC50 values ranging from 0.8 to 40 µM); induces G1 phase cell-cycle arrest, dose-dependent induction of p27Kip1, apoptosis through the mitochondrial pathway, and inhibition of the mTORC1 pathway at 10 µM in pre-T-LBL cells |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | serine/threonine kinases Pim cancers rapamycin-sensitive mammalian target of rapamycin mTORC1 AMPK leukemia inhibitors inhibits inhibition SMI4a SMI 4a cells myeloid lymphoid T-cells T cells lymphoma apoptosis tumors Ser/Thr 438190-29-5 |
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| Gene, Accession, CAS # | CAS: 438190-29-5 |
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| Catalog # | 11029-10 |
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| Price | |
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| Order / More Info | SMI-4a from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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