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Product Name | Chelerythrine chloride |
Description | Cell-permeable. A selective protein kinase C (PKC) inhibitor (IC50 =0.66 µM). Chelerythrine is at least 100-fold more selective for PKCs than for other kinases. It induces apoptotic cell death in polymorphonuclear leukocyte through activation of caspase-3. In addition, Chelerythrine treated cells underwent apoptosis, with features that suggest involvement of the mitochondrial pathway, and through a mechanism that involves inhibition of the anti-apoptotic inhibitor BclXL. MW: 383.82. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride |
Gene, Accession, CAS # | CAS: 3895-92-9 |
Catalog # | 2064-5 |
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Order / More Info | Chelerythrine chloride from BIOVISION, INC. |
Product Specific References | n/a |
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