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| Product Name | Recombinant Human Low-density lipoprotein receptor-related protein 4 |
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| Description | 1747-1905aa; Cytoplasmic Domain. MW: 22kD. Purity >90% as determined by SDS-PAGE. Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.05 mg (Yeast), 0.2 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Multiple epidermal growth factor-like domains 7] |
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| Gene, Accession, CAS # | LRP4, Gene ID: 4038, Accession: NP_002325.2 |
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| Catalog # | MBS1032997 |
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| Order / More Info | Recombinant Human Low-density lipoprotein receptor-related protein 4 from MYBIOSOURCE INC. |
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| Product Specific References | Low density lipoprotein receptor-related protein 10.Ishikawa K., Fujimoto H., Kim D., Saeki S. Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.Nakayama M., Nakajima D., Nagase T., Nomura N., Seki N., Ohara O.Genomics 51:27-34(1998) Human chromosome 11 DNA sequence and analysis including novel gene identification.Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., B |
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