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| Product Name | MTHFS, 1-203aa, Human, His tag, E Coli |
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| Description | MW: 25.4kDa (223aa) confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. MTHFS, also known as 5-formyltetrahydrofolate cyclo-ligase, is a cytosolic protein involved in the formate metabolic process. MTHFS, with a magnesium cofactor, catalyzes the ATP-dependent reaction that reduces 5-formyltetrahydrofolate (5-MTHF) to 5,10-methenyltetrahydrofolate (MTHF). MTHF is the substrate used by MTHFR (methylenetetrahydrofolate reductase) to generate 5-MTHF. MTHF is also a coenzyme used in thymidine biosynthes |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [5-formyltetrahydrofolate cyclo-ligase; Methenyl-THF synthetase] |
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| Gene, Accession, CAS # | MTHFS, Gene ID: 10588, Accession: NP_006432 |
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| Catalog # | MBS203977 |
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| Order / More Info | MTHFS, 1-203aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Field, M.S., et al. (2006) J. Biol. Chem. 281: 4215-4221.; Lim, u., et al. (2007) Blood 109: 3050-3059. |
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