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| Product Name | G1/S-specific cyclin-D1(CCND1) (Human) ELISA Kit |
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| Description | Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity o |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | This ELISA kit is used for quantitative measurement of CCND1 in human serum, plasma, tissue homogenates and other biological fluids. |
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| Other Names | CCND1 (Human) ELISA Kit |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E4287-100 |
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| Order / More Info | G1/S-specific cyclin-D1(CCND1) (Human) ELISA Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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