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| Product Name | Recombinant Human Melanoma antigen preferentially expressed in tumors |
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| Description | 1-509.Full length. MW: 62kD. Purity >90% as determined by SDS-PAGE. Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Opa-interacting protein 4; OIP-4; Preferentially expressed antigen of melanoma] |
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| Gene, Accession, CAS # | PRAME, Gene ID: 23532, Accession: NP_001278644.1 |
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| Catalog # | MBS951713 |
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| Order / More Info | Recombinant Human Melanoma antigen preferentially expressed in tumors from MYBIOSOURCE INC. |
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| Product Specific References | Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor.Ikeda H., Lethe B.G., Lehmann F., van Baren N., Baurain J.-F., de Smet C., Chambost H., Vitale M., Moretta A., Boon T., Coulie P.G.Immunity 6:199-208(1997) A genome annotation-driven approach to cloning the human ORFeome.Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M |
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