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| Product Name | FEN1, 1-380aa, Human, E Coli |
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| Description | MW: 42.5 kDa (380aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to fun |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Flap structure-specific endonuclease 1; FEN-1; MF1; RAD2; Flap structure-specific endonuclease 1 DNase IV; Flap endonuclease 1; Flap structure specific endonuclease 1; hFEN1; Maturation factor 1,] |
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| Gene, Accession, CAS # | FEN1, Gene ID: 2237, Accession: NP_004102 |
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| Catalog # | MBS203445 |
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| Order / More Info | FEN1, 1-380aa, Human, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hakoyama T., et al. (2009) Nature. 462 (7272):514-7. ; Lal A., et al. (2009) Mol Cell. 35 (5):610-25.; |
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