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| Product Name | PCK1, 1-622aa, Human, His tag, E Coli |
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| Description | MW: 71.7 kDa (646aa). Purity >90% by SDS-PAGE. Phosphoenolpyruvate carboxykinase 1, also known as PCK1, is a main control point for the regulation of gluconeogenesis. PCK1 plays an important role in this process by stimulating hepatic glucose production. The expression of PCK1 can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Modulation of the signals governing PCK1 levels presents a potential therapeutic approach to the treatment of Insulin resistance and consequently obes |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Phosphoenolpyruvate carboxykinase 1; Phosphoenolpyruvate carboxykinase 1; PEPCK-C; PEPCK1; PEPCKC] |
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| Gene, Accession, CAS # | PCK1, Gene ID: 5105, Accession: AAH23978 |
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| Catalog # | MBS204560 |
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| Order / More Info | PCK1, 1-622aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Barthel A., et al. (2003) Am J Physiol Endocrinol Metab. 285:685-692.; Wang Y., et al. (1991) J Cell Physiol. 147:374-382. |
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