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Product Name | Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 45kDa. Full Length of Mature Protein: 22-399aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Cholesteryl esterase; Lipase A; Sterol esterase |
Gene, Accession, CAS # | LIPA, UniProt: P38571 |
Catalog # | RPC24795 |
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Order / More Info | Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) from BIOMATIK |
Product Specific References | n/a |
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