| 产品详情 |
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| Product Name | Recombinant Human Integrin-linked kinase-associated serine/threonine phosphatase 2C |
| Description | 1-392aa; Full Length. MW: 58.9kD. Purity >90% as determined by SDS-PAGE. Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation. |
| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [integrin-linked kinase-associated serine/threonine phosphatase 2C; Integrin-linked kinase-associated serine/threonine phosphatase 2C; integrin-linked kinase-associated serine/threonine phosphatase 2C; ILK associated serine/threonine phosphatase] |
| Gene, Accession, CAS # | ILKAP, Gene ID: 80895, Accession: NP_110395.1 |
| Catalog # | MBS1342892 |
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| Order / More Info | Recombinant Human Integrin-linked kinase-associated serine/threonine phosphatase 2C from MYBIOSOURCE INC. |
| Product Specific References | Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.Leung-Hagesteijn C., Mahendra A., Naruszewicz I., Hannigan G.E.EMBO J. 20:2160-2170(2001) Towards a catalog of human genes and proteinssequencing and analysis of 500 novel complete protein coding human cDNAs.Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., |
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