| 产品详情 |
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| Product Name | WT161 |
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| Description | A potent inhibitor of HDAC6 (IC50 = 0.40 nM); selective for HDAC6 over HDAC3 (IC50 = 51.61 nM); induces α-tubulin acetylation, an HDAC6-dependent process, with minimal effect on global lysine acetylation; inhibits growth of patient-derived multiple myeloma cell lines (IC50s = 1.5-4.7 µM); enhances cytotoxicity of bortezomib and carfilzomib against patient-derived multiple myeloma cells; decreases tumor size in a human MM.1S multiple myeloma mouse xenograft model when administered in combination with bortezomib at doses of 50 and 0.5 mg/kg, respectively |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | WT-161 HDAC-6 3 histone deacetylase MM 1S MM1S |
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| Gene, Accession, CAS # | CAS: 1206731-57-8 |
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| Catalog # | 21099-25 |
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| Price | |
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| Order / More Info | WT161 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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