| 产品详情 |
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| Product Name | WT-161 |
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| Description | WT-161 is a potent, selective, and bioavailable HDAC6 (histone deacetylase-6) inhibitor (IC50 0.40 nM). It is selective for HDAC6 over HDAC3 (IC50 = 51.61 nM) and induces α-tubulin acetylation, an HDAC6-dependent process, with minimal effect on global lysine acetylation. WT161 inhibits growth of patient-derived multiple myeloma cell lines with IC50 values ranging from 1.5 to 4.7 µM. WT161 enhances the cytotoxicity of bortezomib (Cat. No. 1846) and carfilzomib (Cat. No. 2385) against patient-derived multiple myeloma cells. MW: 458.56. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (E)-8-(2-(4-(Diphenylamino)benzylidene)hydrazinyl)-N-hydroxy-8-oxooctanamide |
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| Gene, Accession, CAS # | CAS: 1206731-57-8 |
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| Catalog # | B2219-5 |
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| Order / More Info | WT-161 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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