| 产品详情 |
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| Antigenic Specificity | Pannexin 1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 2-4 µg/mL, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Pannexin 1 Polyclonal Antibody. The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation. |
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| Immunogen | n/a |
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| Other Names | PANX1, Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028 |
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| Gene, Accession # | Entrez: 55991; Uniprot: Q9JIP4 |
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| Catalog # | 487900 |
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| Price | |
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| Order / More Info | Pannexin 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24022490, 27159053, 29234270 |
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