| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Store-operated calcium entry-associated regulatory factor |
|---|
| Description | 195-339aa; Cytoplasmic Domain. MW: 31.48kD. Purity >90% as determined by SDS-PAGE. Negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. In response to cytosolic Ca2+ elevation after endoplasmic reticulum Ca2+ refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the app |
|---|
| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [HBV X-transactivated gene 3 protein; HBV XAg-transactivated protein 3; Protein FOAP-7; Transmembrane protein 66] |
|---|
| Gene, Accession, CAS # | SARAF, Gene ID: 51669, Accession: NP_001271168.1 |
|---|
| Catalog # | MBS1301734 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Store-operated calcium entry-associated regulatory factor from MYBIOSOURCE INC. |
|---|
| Product Specific References | SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling.Palty R., Raveh A., Kaminsky I., Meller R., Reuveny E.Cell 149:425-438(2012) Molecular cloning of a human novel gene, FOAP-7, which are highly expressed in macrophages.Fujii Y., Tsuritani K., Yajima Y., Amemiya T., Ukai Y., Naito K., Kawaguchi A., Takayama K.Cloning and identification of human gene 3 transactivated by hepatitis B virus X antigen.Liu Y., Cheng J., Lu Y., Wang G., Zhang L., Chen J., Li |
|---|
| 产品资料 |
|
|