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Product Name | Recombinant Human Store-opeRated calcium entry-associated regulatory factor (SARAF), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 17.5kDa. Cytoplasmic Domain: 195-339aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. In response to cytosolic Ca2+ elevation after endoplasmic reticulum Ca2+ refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca2+ levels, and thus preventing the overload of the cell with excessive Ca2+ ions. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | HBV X-transactivated gene 3 protein; HBV XAg-transactivated protein 3; Protein FOAP-7; Transmembrane protein 66 |
Gene, Accession, CAS # | SARAF, UniProt: Q96BY9 |
Catalog # | RPC25498 |
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Order / More Info | Recombinant Human Store-opeRated calcium entry-associated regulatory factor (SARAF), partial from BIOMATIK |
Product Specific References | n/a |
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