| 产品详情 |
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| Product Name | Tadalafil |
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| Description | A PDE5 inhibitor (IC50 = 1.2 nM); selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 µM); also inhibits PDE11 (IC50 = 11 nM); decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury at 10 mg/kg; reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 240822-07-5 282541-36-0 inhibition cyclic nucleotides intracellular signaling nitric oxide signals transduction vascular PDEs PDE-5 5 five isoforms micromolar pharmacokinetics phosphodiesterase UKs 336017 UK336017 UK-336017 Adcirca Cialis GFs 196960 GF196960 GF-196960 ICs 351 IC351 IC-351 ICOSs ICOS-351 ICOS351 240822-07-5 282541-36-0 |
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| Gene, Accession, CAS # | CAS: 171596-29-5 |
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| Catalog # | 14024-10 |
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| Price | |
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| Order / More Info | Tadalafil from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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