| 产品详情 |
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| Product Name | 6-OHDA (hydrobromide) |
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| Description | A catecholaminergic neurotoxin; has been used to induce dopaminergic lesions and parkinsonian symptoms as a model of Parkinson's disease in rodents; induces locomotor impairment in mice and loss of tyrosine hydroxylase-reactive neurons in mouse brain when administered into the substantia nigra, MFB, or striatum at doses of 9, 6, and 18 µg, respectively; decreases dopamine and norepinephrine levels in rat brain at 200 µg; induces apoptosis in primary rat cortical cells and PC12 rat adrenal cells at 50 µM; activates caspase-3, -8, and -9 in a time-dependent manner and increases the level of intracellular ROS in PC12 cells at 75 µM; induces apoptosis in rat substantia nigra when stereotaxically injected into the right MFB |
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| Size | 250 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,4,5-Trihydroxyphenethylamine|6-hydroxy Dopamine|Oxidopamine |
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| Gene, Accession, CAS # | CAS: 636-00-0 |
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| Catalog # | 25330-250 |
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| Order / More Info | 6-OHDA (hydrobromide) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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