产品详情 |
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Product Name | Recombinant Rat IL-4 Protein |
Description | IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4 T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant rat IL-4 is a 14.0 kDa globular protein containing 126 amino acid residues. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Interleukin-4;IL-4;B-cell IGG differentiation factor;B-cell growth factor 1;B-cell stimulatory factor 1;BSF-1;Lymphocyte stimulatory factor 1;Il4;Il-4; BCGF, BCDF, B cell stimulating factor (BSF-1) |
Gene, Accession, CAS # | Il4, UniProt: P20096 |
Catalog # | PROTP20096-1 |
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Order / More Info | Recombinant Rat IL-4 Protein from BOSTER BIO |
Product Specific References | n/a |
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