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| Product Name | pCAF Inhibitor Screening Kit (Fluorometric) |
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| Description | pCAF (P300/CBP-associated factor, EC 2.3.1.48) also known as K (lysine) acetyltransferase 2B (KAT2B), possesses intrinsic histone acetyltransferase (HAT) activity. pCAF contributes to transcriptional activation by acetylating chromatin and transcription factors through its HAT activity. Deregulated HAT activity plays an important role in various cancers. pCAF inhibitors have potential applications in cancer therapy. pCAF uses both histone 3 (H3) and histone 4 (H4) as substrates. BioVision's pCAF Inhibitor Screening Kit utilizes H3 peptide and Acetyl CoA as the substrates. pCAF acetylates the peptide and generates Coenzyme A with a free thiol group. The CoA is detected using a Thiol Detecting Probe that reacts with thiol groups and gives enh |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Screening/studying/characterizing potential inhibitors of pCAF |
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| Other Names | P300/CBP-associated factor Inhibitor Screening Kit (Fluorometric), K (lysine) acetyltransferase 2B Inhibitor Screening Kit (Fluorometric), KAT2B Inhibitor Screening Kit (Fluorometric) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K345-100 |
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| Price | |
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| Order / More Info | pCAF Inhibitor Screening Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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