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| Product Name | Recombinant Human Integrin alpha-2 |
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| Description | 188-365aa; Partial. MW: 35.63kD. Purity >90% as determined by SDS-PAGE. Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [CD49 antigen-like family member B Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD_antigen: CD49b] |
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| Gene, Accession, CAS # | ITGA2, Gene ID: 3673, Accession: NP_002194.2 |
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| Catalog # | MBS961599 |
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| Order / More Info | Recombinant Human Integrin alpha-2 from MYBIOSOURCE INC. |
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| Product Specific References | The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.Takada Y., Hemler M.E.J. Cell Biol. 109:397-407(1989) |
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