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| Product Name | Recombinant Human Integrin alpha-IIb |
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| Description | 639-887aa; Partial. MW: 42.97kD. Purity >90% as determined by SDS-PAGE. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platel |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41] |
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| Gene, Accession, CAS # | ITGA2B, Gene ID: 3674, Accession: NP_000410.2 |
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| Catalog # | MBS956218 |
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| Order / More Info | Recombinant Human Integrin alpha-IIb from MYBIOSOURCE INC. |
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| Product Specific References | Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors.Poncz M., Eisman R., Heidenreich R., Silver S.M., Vilaire G., Surrey S., Schwartz E., Bennett J.S.J. Biol. Chem. 262:8476-8482(1987) GPIIb and GPIIIa amino acid sequences deduced from human megakaryocyte cDNAs.Frachet P., Uzan G., Thevenon D., Denarier E., Prandini M.H., Marguerie G.Mol. Biol. Rep. 14:27-33(1990) Organization of the gene for platelet glycoprot |
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