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Product Name | FOXP1, Recombinant, Human, aa1-114, GST-Tag (Forkhead Box Protein P1) |
Description | Purity ~90% (SDS-PAGE). Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity; may promote midbrain identity in embryonic stem cell-derived dopamine neurons by regulating PITX3. Negative |
Size | 10ug, 50ug, 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | Mac-1-regulated forkhead1 |
Gene, Accession, CAS # | SwissProt: Q9H334 |
Catalog # | 373362 |
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Order / More Info | FOXP1, Recombinant, Human, aa1-114, GST-Tag (Forkhead Box Protein P1) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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