| 产品详情 |
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| Product Name | FOXQ1 |
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| Description | Highly purified (HPLC, MS). Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via this protein. The Forkhead family of transcription factors is involved in tumorigenesis in rhabdomyosarcoma and acute leukemias (1-3). Within the family, three members (FKHR, AFX and FKHRL1) have sequence similarity to the nematode homologue DAF-16, which has been shown to mediate signaling via a pathway involving IGFR1, PI3K and Akt (4-6). There are three Akt phosphorylation sites in the FKHR proteins: Thr24, Ser256 and Ser319. Phosphorylation of FKHR family members at these sites by Akt promotes cell survival and regulates the cell cycle. Phosphorylation regulates FKHR nuclear translocation and target gene transcription (7,8). Sequence (linear): RRPGPHLPYPVE Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | ELISA IC IHC IP WB |
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| Other Names | FOXQ1 (Forkhead box Q1, FKHRL1, Hepatocyte Nuclear Factor 3 Forkhead, HFH1, Winged Helix/Forkhead Transcription Factor) Control Peptide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | F9050-26P |
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| Price | |
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| Order / More Info | FOXQ1 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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