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| Product Name | lktA, Recombinant, Pasteurella Haemolytica, aa715-953, GST-Tag (Leukotoxin) |
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| Description | Purity ~90% (SDS-PAGE). Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca2+ and lysis of the host cell. This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak holytic activity. Source: Recombinant protein corresponding to aa715-953 from pasteurella haemolytica IktA, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~53kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P0C085 |
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| Catalog # | 374055 |
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| Order / More Info | lktA, Recombinant, Pasteurella Haemolytica, aa715-953, GST-Tag (Leukotoxin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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